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These clinical observations were further substantiated by a proteomic analysis showing that semaglutide treatment reverted the circulating proteome of MASH patients to a pattern similar to that of healthy individuals, implicating changes in metabolism, inflammation, and fibrosis-related proteins

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This development wont just affect drugmakers it will also have impacts on medical device manufacturers (medtech), insurance coverage, consumer behavior and overall public health

For comparison, only 8.6% of patients treated with liraglutide generated antibodies, which can be explained by the higher sequence homology with GLP-1 [160]