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XPP treatment altered expression of genes involved in B cell differentiation and plasma cell IgE production, including cyclin d1 (CCND1), dual specificity phosphatase 4 (DUSP4), syndecan -1 (SDC1), erythroblastosis virus proto-oncogene 1 (ETS1), protein tyrosine phosphatase, receptor type, C (PTPRC), and IL-6R (Fig

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Sulforaphane exposure led to reduction in cell growth, by significantly downregulating key cell cycle-related genes in HepG2 and Huh7 cell lines, and also within a xenograft mouse model (Sato et al., 2018)

Multi-omics dissection of tumor microenvironment-mediated drug resistance: mechanisms and therapeutic reprogramming