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Danuglipron, an oral glucagon-like peptide-1 (GLP-1) receptor agonist, will undergo dose optimization studies in the second half of 2024 as Pfizer seeks to evaluate multiple doses of the formulation which they hope will inform the registration-enabling studies

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The goal is to provide meaningful insight without unnecessary testing

2 Add appropriate volume based on research protocol

"The REIMAGINE 1-3 studies showed promising results by combining a novel amylin analog with the proven significant effects of semaglutide for HbA 1c reduction and weight loss in adults living with type 2 diabetes," said Martin Holst Lange, executive vice president, chief scientific officer and head of Research and Development at Novo Nordisk