The tumor suppressor p53 limits ferroptosis by blocking DPP4 activity
Johnson 5 , (1)Department of Medicine, George Washington University Hospital, Washington, DC, (2)Alexandria University Faculty of Medicine, Alexandria, Egypt, (3)The George Washington University School of Medicine and Health Sciences, (4)George Washington University Medical Faculty Associates, (5)Department of Surgery, George Washington University Medical Faculty Associates, (6)Department of Endocrinology, George Washington University Medical Faculty Associates Background: Nonalcoholic fatty liver disease (NAFLD) is prevalent in up to 60% of patients with type 2 diabetes mellitus (T2DM)
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For instance, forms of several B vitamins, including thiamin, riboflavin, niacin, and pantothenic acid, as well as the compound lipoic acid, are utilized in reactions that completely metabolize glucose to carbon dioxide and water (3)
