Bottom Line DSIP shows promise as a sleep and recovery aid, but the lack of long-term human data means its use should be approached with caution
This plan may include Retatrutide therapy along with other complementary treatments
Weekly injectable semaglutide (Wegovy): Weekly injectable tirzepatide (Zepbound): $299 for starter doses and $449 or more per month for full-strength doses when purchased directly from the manufacturer or through pharmacies and partners such as Walmart Resources We Trust Cleveland Clinic: GLP-1 Agonists JAMA Internal Medicine: I Am Taking a GLP-1 Weight-Loss Medication What Should I Know
The primary outcome measure was a composite of death from cardiovascular causes, nonfatal MI or nonfatal stroke in a time-to-first-event analysis
On one hand, the lack of approval means no established treatment protocols exist, insurance will not cover costs, and medical supervision may be limited
Interestingly, P9 supplementation to a HFD does not increase plasma GLP-1 in Il6 / mice (Yoon et al., 2021)