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Individual safety findings for one molecule dont necessarily predict class-wide effects, says Finer, safety signals often relate to specific structural features or off-target activities rather than the primary mechanism of action. He thinks oral GLP-1 drugs have the potential for better dose titration, which might help control the current, mainly gastrointestinal, side-effects of the injectable peptides
Whilst the early data for retatrutide is encouraging, it remains a research compound and is not yet proven safe and effective to the standard required for routine clinical use
doi: 10.3803/EnM.2017.32.2.248
Prepare the injection pen
SIBO stands for small intestinal bacterial overgrowth
