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For Smith-Reed, relief came in the form of a synthetic peptide known as PT141, also called bremelanotide

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The medications' effects on appetite regulation and satiety might also play an indirect role, as some individuals report that reduced overall appetite extends to diminished desire for alcohol

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While GIP indeed acts as an incretin in healthy individuals, researchers found an important limitation in patients with type 2 diabetes, GIP loses most of its insulinotropic efficacy (the pancreatic cells become GIP-resistant) ( [32] )