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The SLC7A11/GSH/GPx4 axis plays a central role in the cells defense against ferroptosis, with GPx4 utilizing glutathione (GSH) as a cofactor to reduce toxic lipid peroxides at the plasma membrane, thereby protecting the cell from ferroptosis

Akhavan, O., Ghaderi, E., & Rahighi, R

Transl Res 168:146160

Below, we introduce the different types and their intricate mechanisms of oxidative cell death

These lipids suggest increased dependence on de novo synthesis, as they are highly enriched in breast cancer tumors [24]

Studies were eligible if they reported published data in English relevant to endometriosis and at least one of the targeted cell-death modalities, with specific attention to Erastin or its analogs in in-vitro, ex-vivo, in-vivo, or human observational contexts