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For example, a 2025 JAMA Network Open cohort found semaglutide/tirzepatide users had lower risks of dementia, stroke, and all-cause mortality

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For short-term management of Mounjaro-related nausea, antiemetics may be considered with important UK safety restrictions: domperidone has cardiac/QT interval prolongation risks (use lowest dose, shortest duration, avoid in cardiac risk patients) and metoclopramide is limited to maximum 5 days use in adults due to extrapyramidal side effect risks

Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

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Front Physiol (2022) 13:770375