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The use of these pouches is only second to e-cigarettes, but e-cigarette use was declining while nicotine pouch use was "low and stable." Notably, the pouches are not approved by the FDA as nicotine replacement products helping people to quit smoking, such as Nicorette gum
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[21] Unlike over-the-counter NRT products, these prescription medications are best used on their own, rather than in combination with other products, unless your doctor gives you express approval to combine NRT products