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The effect of semaglutide on body weight over liraglutide was similar to that in the phase 2 trial in obesity, 9 while the placebo-adjusted weight loss and adverse effect profiles were similar to that in STEP 1 for semaglutide 2 and in SCALE Obesity and Prediabetes for liraglutide

In summary, CS is a versatile candidate for developing sustained-release peptide delivery systems in joint applications

These physiological observations, in addition to person-level studies, suggest that GLP-1 drugs could represent an entirely new pathway for treating mental health conditions

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In one embodiment of the present invention, the mass ratio of water to organic solvent in the reagent used for controlling the reaction pH in step (1) is 1 to 5:1 to 5