doi: 10.3389/fcell.2025.1737456 Received 01 November 2025 Revised 14 December 2025 Accepted 22 December 2025 Published 12 January 2026 Volume 13 - 2025 Edited by Silvia Masciarelli, Sapienza University of Rome, Italy Reviewed by Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Weibei Sheng, Peking University, China Updates Copyright 2026 Zhang, Li, Yang and Yang
PMID 25195560
Moreover, variation in the angiotensin II type 1 receptor has been linked with depression diagnosis and frontotemporal brain volumes (69)
Safety of L-Carnitine Carnitine is relatively well-tolerated but in high doses it may increase levels of trimethylamine-N-oxide (TMAO), a compound linked with an heart disease since it can increase blood pressure and the formation of plaque within the artery walls (atherosclerosis) (9)
Conclusions: This study confirms that plasma carnitine concentrations decline in the course of pregnancy, an effect that can be prevented by the supplementation of carnitine
The short answer is that for most people, B12 injections given in a medical setting have a strong safety record
