Absolute contraindications to GLP-1 receptor agonists include: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 Previous serious hypersensitivity reaction to the specific GLP-1 drug Pregnancy and breastfeeding (for medications approved for weight management: Wegovy, Saxenda, and Zepbound) Patients should maintain age-appropriate cancer screening regardless of GLP-1 use
Added Dr Ee: In our practice, patients do conceive successfully when they manage to lose weight effectively, regardless of whether it is through diet, exercise, medication or bariatric surgery. Dr Khoo Chin Meng, who heads the division of endocrinology at National University Hospital, also does not recommend the use of Ozempic to boost fertility
Browse all Peptides and GLP-1 education The "Retatrutide online" search is usually about access: whether retatrutide can be prescribed by telehealth, whether online sellers are legitimate, what clinical-trial access looks like, and what safer alternatives may exist
They work by regulating appetite, slowing digestion, and improving blood sugar control
Its costing us $1.5 million a year
Gray-market peptides sold as research chemicals are not manufactured to pharmaceutical standards