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Cysteine levels in the supernatant were measured by a Cysteine Assay Kit (#MAK255, Sigma) and the cysteine standards

Proceedings from the National Academy of Sciences of the United States of America, 114 (14), 3750-3755

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Smoking and alcohol consumption can also speed up this depletion process

Methylenetetrahydrofolate dehydrogenase ( MTHFD1 ) MTHFD1 is a trifunctional enzyme of pivotal importance in the interconversion of folate cofactors for either nucleic acid synthesis or hcy remethylation reactions (Figure 1)

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