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However, test-tube and animal studies show that guarana extract may boost metabolism and limit fat cell production by suppressing certain genes ( Side effects: Because guarana is high in caffeine, it may cause insomnia, headaches, nervousness and increased heart rate and anxiety, especially when taken in high doses ( Summary Guarana which is especially high in caffeine may boost metabolism, but more research is needed to determine whether it suppresses appetite or promotes weight loss

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Pregnant women exposed to lead may face increased risks of miscarriage, preterm birth, and developmental disorders in infants (PubMed Study)