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Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion

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Apigenin is a naturally occurring flavonoid that is found in plants and taken commonly as a supplement

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However, a review of recent studies indicates that this is soon to change as more clinicians become aware of the unique advantages of nasal delivery of peptides and other therapeutics

The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis