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For patients experiencing muscle discomfort or weakness while taking GLP-1 medications, several evidence-based strategies can help minimize symptoms while maintaining the therapeutic benefits of treatment

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Inhibited adipogenesis in aging adipose tissue White adipose tissue (WAT) is the primary storage location of excess nutritional energy in the form of triglycerides (TAGs), with a critical role in metabolic homeostasis

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Furthermore, a retrospective analysis of a Chinese cohort of knee OA patients with type 2 diabetes, those patients who had been prescribed a GLP-1 agonist (including liraglutide, semaglutide or other), exhibited reduced cartilage volume loss after 2 years, compared to those patients who had not been prescribed a GLP-1 agonist [78]

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