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Studies in mice demonstrated that liraglutide-induced C-cell proliferation was dependent on the GLP-1 receptor and that liraglutide did not cause activation of the REarranged during Transfection (RET) proto-oncogene in thyroid C-cells

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Despite not being at liberty to disclose too many details regarding the investigation, Bradner said that the analysis of the dataset highlights the medicines differentiated profile, giving Amgen confidence to enter into final Phase III planning and opening a Phase II clinical trial for the study of diabetes

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