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The next day, cells were exposed to 2 mM aspirin (ASA) and/or 20 M V-9302 under 20% O 2 (normoxic: NO) and 1% O 2 (hypoxic: HY) conditions, with each drug diluted in a total volume of 200 L

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930 TRPM2 induces mitochondrial lipid peroxidation in hepatic I/R injury by increasing the expression of ALOX12, and TRPM2 inhibitors or calcium depletion significantly mitigate ferroptosis caused by hepatic IR injury both in vitro and in vivo