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Additionally, this use is off-label, and current evidence is limited, inconsistent, and not approved by major regulatory authorities such as the U.S

184 Some members of the TRIM family contain a COS box which is located immediately downstream of the coiled-coil domain

DSIP has been shown to influence neurotransmitter levels, including serotonin (5-HT), glutamate, dopamine, and melatonin, which are crucial for sleep regulation 2

Chem Res Toxicol 27:514523

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